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South Sudan
Risk:
Very High
Health Overview
South Sudan Level 4 where armed conflict ongoing, landmines cause casualties, non-emergency U.S. personnel departed March 2025. Healthcare among most limited on Earth. No paved roads outside Juba, no ambulance, no emergency number.
Key Health Risks
High
Malaria
Hyperendemic chloroquine-resistant P. falciparum year-round including Juba.
Very High
Armed Conflict / Landmines
Active armed conflict. Landmines unmarked. Roads unsafe. Aid workers targeted.
High
Meningococcal Disease
Meningitis belt. MenACWY strongly recommended. Meningitis without ICU rapidly fatal.
Health Risk Callout
Highest TB globally. Kala-azar endemic fatal without treatment. Polio — booster mandatory. No ambulance.
Other Health Risks
Meningococcal; Cholera; Typhoid; Rabies; TB; Polio; Kala-azar; Schistosomiasis | 2026 UPDATE: Ebola (regional): 2026 Ebola outbreak in neighboring DR Congo (Bundibugyo virus); cited in the current South Sudan State Dept advisory and tracked by WHO/CDC. Regional risk relevant to South Sudan itineraries. (https://www.who.int/emergencies/situations/ebola-outbreak---drc-2026, 2026) ; Cholera: Ongoing cholera outbreak in South Sudan with sustained response through 2026 per WHO AFRO. (https://www.afro.who.int/countries/south-sudan/news/sustained-response-curbing-cholera-outbreak-south-sudan, 2026)
Regional Information
Regional Risk Callout
Risk extreme throughout. Juba most functional but armed robbery. Outside Juba: ambushes, cattle raiding. Landmines scattered unmarked.
Regional Healthcare Callout
No capacity outside Juba. Medevac to Nairobi (AMREF). FAA NOTAM/SFAR.
Vaccine and Malaria Prevention
💉 Entry Vaccine Required
Yellow fever certificate required for all travelers.
🛡️ Recommended Vaccines
Routine; YF (required); Hep A; Hep B; Typhoid; Rabies; Polio booster (required); Cholera; Meningococcal (meningitis belt — essential Dec-Jun)
🦟 Malaria Information
- Risk Level: High
- Areas: All areas year-round; highest during/after wet season May-October
- Recommended Drug: Atovaquone-proguanil; doxycycline; mefloquine; tafenoquine
- Drug Resistance: Yes
P. falciparum chloroquine-resistant hyperendemic including Juba. Top cause of death.
High
Physician Note
Dr. Robert
Emergency Medicine · 25+ Years · 40+ Countries
Medevac plan first, vaccines second. Meningococcal non-negotiable. Polio booster required.
YF hard requirement. Landmine trauma kit with tourniquet. Kala-azar on post-travel differential.
Pre-Departure Checklist
8+ Weeks
- DO NOT TRAVEL HERE
Trip Type Guidance
No trip types appropriate. Only authorized NGO/UN with landmine-aware planning.
Notes
Special Evacuation Notes
Non-emergency staff departed March 2025. FAA NOTAM. Medevac to Nairobi (AMREF) or Entebbe. Landmine risk.
Safety Notes
Active conflict. Landmines. Aid workers targeted. Strict curfew. Journalists killed.
partner recommendation
Medical Evacuation & Assistance
A medical crisis far from home can cost $50,000+ to evacuate. Global Rescue — the partner we personally trust — provides worldwide evacuation and round-the-clock medical assistance.
Good For
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