Niger

Health Overview
Key Health Risks
Health Risk Callout
Other Health Risks
Regional Information
Vaccine and Malaria Prevention
- Risk Level: High
- Areas: Country-wide; all regions; year-round
- Recommended Drug: Atovaquone-proguanil; Doxycycline; Mefloquine; Tafenoquine
- Drug Resistance: Yes
P. falciparum hyperendemic; chloroquine-resistant. Malaria cited in Health risk indicator. Healthcare outside Niamey essentially absent. Carry standby Coartem.
Physician Note
Niger carries five risk indicators simultaneously, including Health — which at Level 4 means the basic care needed to keep a patient alive while awaiting medevac may not be available. A US citizen was kidnapped from their own home in Niamey in October 2025, so the capital is no longer a safe haven, and reports of passport confiscation at the airport are alarming for anyone planning an exit.
The diphtheria situation is a reminder of how fast vaccine-preventable disease returns when health systems are disrupted. Niger is one of eight countries in a West and Central African outbreak that has passed 29,000 suspected cases and 1,420 deaths since the start of 2025, with a case fatality ratio around 5-6% and 34 of Niger's 72 districts affected. Two things make that worse than the numbers look: laboratory confirmation is limited by diagnostic shortages, and diphtheria antitoxin is in global short supply, so severe disease may not be treatable where it occurs. Confirming a Tdap booster is the single highest-value preparation. For legitimate humanitarian travelers, comprehensive preparation is what separates a manageable trip from a catastrophe. Be sure to consult your Dr. prior to travel to discuss.
Pre-Departure Checklist
8+ Weeks
- DO NOT TRAVEL
- Be sure to consult your Dr. prior to travel to discuss
- CDC recommends Full vaccines (YF; MenACWY+B; Tdap — diphtheria outbreak; Typhoid; Hep A/B; Rabies PrEP; Polio booster)
- Malaria prophylaxis + standby Coartem
- K&R insurance
- Medevac membership.
2-4 Weeks
- STEP
- Military escort arrangements
- Passport confiscation plan
- Will/POA.
Day Of
- Police 17
- SAMU 15
- Embassy +(227) 99-49-90-66
- Active check-in schedule.
Trip Type Guidance
Mission/humanitarian only: experienced workers through UN/ICRC/MSF with dedicated security. US Embassy itself has ordered non-emergency departure.

